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Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes  for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry

A unique natural selective kappa-opioid receptor agonist, salvinorin A, and  its roles in human therapeutics - ScienceDirect
A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics - ScienceDirect

Effects of Kappa Opioid Agonists on Cocaine- and Food-Maintained Responding  by Rhesus Monkeys | Journal of Pharmacology and Experimental Therapeutics
Effects of Kappa Opioid Agonists on Cocaine- and Food-Maintained Responding by Rhesus Monkeys | Journal of Pharmacology and Experimental Therapeutics

An updated assessment of the translational promise of G-protein-biased kappa  opioid receptor agonists to treat pain and other indications without  debilitating adverse effects - ScienceDirect
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Effects of the kappa opioid receptor agonist nalfurafine on IFN-γ⁺CD4⁺... |  Download Scientific Diagram
Effects of the kappa opioid receptor agonist nalfurafine on IFN-γ⁺CD4⁺... | Download Scientific Diagram

Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and  Back
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back

Opioids in cancer: The κ‑opioid receptor (Review)
Opioids in cancer: The κ‑opioid receptor (Review)

Molecular mechanism of biased signaling at the kappa opioid receptor |  Nature Communications
Molecular mechanism of biased signaling at the kappa opioid receptor | Nature Communications

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for  the Development of Potential Treatments of Pain with Reduced Side Effects
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects

BRL 52537 hydrochloride, kappa-opioid agonist (CAS 112282-24-3) (ab120669)
BRL 52537 hydrochloride, kappa-opioid agonist (CAS 112282-24-3) (ab120669)

Will peripherally restricted kappa‐opioid receptor agonists (pKORAs)  relieve pain with less opioid adverse effects and abuse potential? -  Albert‐Vartanian - 2016 - Journal of Clinical Pharmacy and Therapeutics -  Wiley Online Library
Will peripherally restricted kappa‐opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential? - Albert‐Vartanian - 2016 - Journal of Clinical Pharmacy and Therapeutics - Wiley Online Library

Kappa Receptors – Opioid Peptides
Kappa Receptors – Opioid Peptides

Kappa Receptors – Opioid Peptides
Kappa Receptors – Opioid Peptides

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Opioid Receptor | kappa, mu Opioid Receptor
Opioid Receptor | kappa, mu Opioid Receptor

Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid  Receptor Agonists - Yadav - 2021 - ChemMedChem - Wiley Online Library
Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists - Yadav - 2021 - ChemMedChem - Wiley Online Library

Pharmaceuticals | Free Full-Text | Therapeutic Potential of Kappa Opioid  Agonists
Pharmaceuticals | Free Full-Text | Therapeutic Potential of Kappa Opioid Agonists

EX-99.2
EX-99.2

Structure–activity relationship investigation of triazole-based kappa  opioid receptor agonists | SpringerLink
Structure–activity relationship investigation of triazole-based kappa opioid receptor agonists | SpringerLink

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Topical administration of the kappa opioid receptor agonist nalfurafine  suppresses corneal neovascularization and inflammation | Scientific Reports
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports